Ralph Metzner's book Ayahuasca: Human Consciousness and the Spirits of Nature (1st edition) and Sacred Vine of Spirits: Ayahuasca (2nd edition) is an excellent overview of modern conceptions of Ayahuasca and where and how they originated.
The book starts off with a brief history of the available data on this most powerful of entheogens. Next Metzner delves into modern trip reports of the experience by mostly well-to-do professionals, doctors, psychiatrists, etc. In this section, the book does tend to get a little fluffy and new agey in its descriptions. Here, too, I was disappointed that he did not offer/include indigenous descriptions of the experience.
While at first this book had difficulty drawing me in, it wasn't until the end of the trip reports section, probably around page 150, that a startling story, so identical to one of my own, really grabbed my attention into the book as a whole. The stories previous to this one were also similar to my own, as I have seen the snakes, etc., myself, however the other stories often didn't draw me in as this one in particular had as it twisted around my soul like a boa.
About 2/3 into the book it becomes clear why Metzner has chosen these particular stories. He uses the stories to show a sort of universal archetypal imagery found within the experiences as well as using them to show the overall personal benefits and healings gained by each individual's direct experiences with the sacred brew. He makes especially clear the importance of "la purga" or the purge, which are the effects of Ayahuasca to cause vomiting to cleanse the body and soul. However, I questioned if this was done while possibly omitting negative reports, not of trips, but of Kanaima related issues (see Dr. Neil Whitehead). Though I must admit that my own numerous experiences were indeed along the same lines of self-recognition and self-responsibility laid out in the work.
Next Metzner calls on the famed Dr. Dennis McKenna to break down the chemistry and history of Ayahuasca, as McKenna with his brother Terence were pioneers in the research on DMT and Ayahuasca. Next Metzner calls on Dr. Charles Grob and Dr. John Callaway to give an excellent (yet self limited) history on Ayahuasca from its studies to its effects on human psychological behavior, drug addiction, etc. Finally he ends the book with a well thought out and in some places admittedly speculative conclusion on the possibilities to the fulfilling of human consciousness on a Gaian or global scale.
Not the most profound read, but well worth the read. I'd give it a strong 4.5 star. A necessary addition to any ethnopharmacological library.